Publications and Projects

Anna Cuscó, Carlotta Catozzi, Joaquim Viñes, Armand Sánchez, Olga Francino. Microbiota profiling with long amplicons using Nanopore sequencing: full-length 16S rRNA gene and whole rrn operon. bioRxiv Oct. 24, 2018; doi: http://dx.doi.org/10.1101/450734.

Natalia Sastre, Oriol Calvete Jessica Martínez-Vargas, Nuria Medarde, Joaquim Casellas, Laura Altet, Armand Sánchez, Olga Francino, Jacint Ventura. (2018)  Skin mites in mice (Mus musculus): high prevalence of Myobia sp. (Acari, Arachnida) in Robertsonian mice. Parasitology Research 117: 2139–2148

Soler C, Goossens T, Bermejo A, Migura- García L, Cusco A, FrancinoO, et al.(2018) Digestive microbiota is different in pigs receiving antimicrobials or a feed additive during the nursery period. PLoS ONE 13(5): e0197353. https://doi. org/10.1371/journal.pone.0197353

Anna Cusco; Janelle M Belanger; Liza Gershony; Alma Islas-Trejo; Kerinne Levy; Juan F Medrano; Armand Sánchez; Anita M. Oberbauer; Olga Francino. Individual signatures and environmental factors shape skin microbiota on healthy dogs. Microbiome. 2017 Oct 13;5(1):139. doi: 10.1186/s40168-017-0355-6.

Catozzi C, Sanchez Bonastre A, Francino O, Lecchi C, De Carlo E, Vecchio D, Martucciello A, Fraulo P, Bronzo V, Cuscó A, D’Andreano S, Ceciliani F. The microbiota of water buffalo milk during mastitis. PLoS One. 2017 Sep 19;12(9):e0184710. doi: 10.1371/journal.pone.0184710. eCollection 2017.

Anna Cusco, Joaquim Vines, Sara D’Andreano, Francesca Riva, Joaquim Casellas, Armand Sanchez, Olga Francino. 2017. Using MinION to characterize dog skin microbiota through full-length 16S rRNA gene sequencing approach. bioRxiv 167015; doi: https://doi.org/10.1101/167015

Anna Cuscó Martí, Armand Sanchez Bonastre, Laura Altet, Lluis Ferrer and Olga Francino. Individual Signatures Define Canine Skin Microbiota Composition and Variability. Front. Vet. Sci., 06 February 2017 doi.org/10.3389/fvets.2017.00006

Cuscó A, Sánchez A, Altet L, Ferrer L, Francino O. Corrigendum: Individual Signatures Define Canine Skin Microbiota Composition and Variability. Front Vet Sci. 2017 Jul 28;4:119. doi: 10.3389/fvets.2017.00119. eCollection 2017.

Sara D’Andreano , Armand Sànchez Bonastre , Olga Francino , Anna Cuscó Martí, Cristina Lecchi, Guido Grilli, Davide Giovanardi, Fabrizio Ceciliani. Gastrointestinal microbial population of turkey (Meleagris gallopavo) affected by Haemorrhagic Enteritis virus. Poult Sci. 2017 Oct 1;96(10):3550-3558. doi: 10.3382/ps/pex139.

Sastre N, Francino O, Curti JN, Armenta TC, Fraser DL, Kelly RM, Hunt E, Silbermayr K, Zewe C, Sánchez A, Ferrer L. Detection, Prevalence and Phylogenetic Relationships of Demodex spp and further Skin Prostigmata Mites (Acari, Arachnida) in Wild and Domestic Mammals. PLoS One. 2016 Nov 1;11(11):e0165765. doi: 10.1371/journal.pone.0165765.

Roura X, et al., Polymerase chain reaction detection of Bartonella spp. in dogs from Spain with blood culture-negative infectious endocarditis, Journal of Veterinary Cardiology (2018), https://doi.org/10.1016/ j.jvc.2018.04.006

Nashat M, Ricart Arbona R, Riedel ER, Francino O, Ferrer L, Luchins KR, Lipman NS. 2018. A comparison of diagnostic methods and sampling sites for the detection of Demodex musculi. Journal of the American Association for Laboratory Animal Science. JAALAS 57: 1-13.

Tabar MD, Movilla R, Serrano L, Altet L, Francino O, Roura X. PCR evaluation of selected vector-borne pathogens in dogs with pericardial effusion. J Small Anim Pract. 2018 Apr;59(4):248-252. doi: 10.1111/jsap.12817.

Aitor Cevidanes, Laura Altet, Andrea D. Chirife, Tatiana Proboste and Javier Millán. Drivers of Bartonella infection in micromammals and their fleas in a Mediterranean peri-urban area. Veterinary Microbiology 2017. http://dx.doi.org/10.1016/j.vetmic.2017.03.023

Movilla R, Altet L, Serrano L, Tabar MD, Roura X. Molecular detection of vector-borne pathogens in blood and splenic samples from dogs with splenic disease. Parasit Vectors. 2017 Mar 13;10(1):131. doi: 10.1186/s13071-017-2074-z.

Tabar MD, Altet L, Maggi RG, Altimira J, Roura X. First description of Bartonella koehlerae infection in a Spanish dog with infective endocarditis. Parasit Vectors. 2017 May 19;10(1):247. doi: 10.1186/s13071-017-2188-3.

Zewe CM, Altet L, Lam ATH, Ferrer L. Afoxolaner and fluralaner treatment do not impact on cutaneous Demodex populations of healthy dogs. Vet Dermatol. 2017 Oct;28(5):468-e107. doi: 10.1111/vde.12453.

Maia C, Altet L, Serrano L, Cristóvão JM, Tabar MD, Francino O, Cardoso L, Campino L, Roura X. Molecular detection of Leishmania infantum, filariae and Wolbachia spp. in dogs from southern Portugal. Parasites & Vectors. 2016 May 10;9(1):170. doi: 10.1186/s13071-016-1452-2.

Solano-Gallego L., Di Filippo L., Ordeix L., Planellas M., Roura X., Altet L., Martínez-Orellana P, Montserrat S. Early reduction of Leishmania infantum-specific antibodies and blood parasitemia during

treatment in dogs with moderate or severe disease. Parasites & Vectors. 2016 , 9, 235. http://doi.org/10.1186/s13071-016-1519-0

Millán J, Proboste T, Fernández de Mera IG, Chirife AD, de la Fuente J, Altet L. Molecular detection of vector-borne pathogens in wild and domestic carnivores and their ticks at the human-wildlife interface. Ticks Tick Borne Dis. 2016 Mar;7(2):284-90. doi: 10.1016/j.ttbdis.2015.11.003. Epub 2015 Nov 18.

Millán J, Chirife AD, Altet L. Serum chemistry reference values for the common genet (Genetta genetta): variations associated with Leishmania infantum infection. Vet Q. 2015 Mar;35(1):43-7. doi: 10.1080/ 01652176. 2014.987883. Epub 2014 Dec 11.

Tatiana Proboste, Gladys Kalema-Zikusoka, Laura Altet, Laia Solano-Gallego, Isabel G. Fernández de Mera, Andrea D. Chirife, Jesús Muro, Ester Bach, Antonio Piazza, Aitor Cevidanes, Valeria Blanda, Lawrence Mugisha, José de la Fuente, Santo Caracappa and Javier Millán. Infection and exposure to vector-borne pathogens in rural dogs and their ticks, Uganda. Parasites & Vectors 2015 Jun 5;8(1):306.

Pennisi M-G, Persichetti M-F, Serrano L, Altet L, Reale S, Gulotta L, et al. Ticks and associated pathogens collected from cats in Sicily and Calabria (Italy). Parasit Vectors. 2015;8:512.

Ferreira D, Sastre N, Ravera I, Altet L, Francino O, Bardagí M, Ferrer L. Identification of a third feline Demodex species through partial sequencing of the 16S rDNA and frequency of Demodex species in 74 cats using a PCR assay. Veterinary Dermatology 26(4):239-e53 · August 2015

Millán J, Proboste T, Fernández de Mera IG, Chirife AD, de la Fuente J, Altet L. Molecular detection of vector-borne pathogens in wild and domestic carnivores and their ticks at the human-wildlife interface. Ticks Tick Borne Dis. 2016 Mar;7(2):284-90. doi: 10.1016/j.ttbdis.2015.11.003. Epub 2015 Nov 18.

Iván Ravera, Laura Altet, Olga Francino, Armand Sánchez, Wendy Roldán, Sergio Villanueva, Mar Bardagí and Lluís Ferrer. Small Demodex populations colonize most parts of the skin of healthy dogs. Veterinary Dermatology 2013, 24: 168-173

Vilhena H, Martínez-Díaz VL, Cardoso L, Vieira L, Altet L, Francino O, Pastor J and Silvestre-Ferreira AC. Feline vector-borne pathogens in the north and centre of Portugal. Parasites & Vectors 2013, 6:99

M.D. Tabar, L. Altet, V. Martínez and X. Roura. Wolbachia, filariae and Leishmania coinfection in dogs from a Mediterranean area. Journal of Small Animal Practice (2013), 54 (4): 174-178

Verónica L Martínez-Díaz, Ana Cristina Silvestre-Ferreira, Hugo Vilhena, Josep Pastor, Olga Francino and Laura Altet. Prevalence and co-infection of haemotropic mycoplasmas in Portuguese cats by real-time polymerase chain reaction. Published online 12 March 2013 Journal of Feline Medicine and Surgery. DOI: 10.1177/1098612X13480985

  1. Sastre, I. Ravera, D. Ferreira, L. Altet, A. Sanchez, M. Bardagí, O. Francino, L. Ferrer Development of a PCR technique specific for Demodex injai in biological specimens. Parasitol Res DOI 10.1007/s00436-013-3531

Mireia Fernandez, Laura Altet, Veronica L. Martinez-Diaz, Maria-Dolores Tabar, Paolo Silvestrini, Olga Francino, Xavier Roura. Assessment of PCR status of vector-borne pathogens in dogs presenting arrhythmias. Comp Clin Pathol 2013, DOI 10.1007/s00580-013-1803-8

Javier Cabello, Laura Altet, Constanza Napolitano, Natalia Sastre, Ezequiel Hidalgo, José Antonio Dávila, Javier Millán. Survey of infectious agents in the endangered Darwin’s fox (Lycalopex fulvipes): High prevalence and diversity of hemotrophic mycoplasmas. Veterinary Microbiology 2013, 167: 448–454.

Iván Ravera, Laura Altet, Olga Francino, Armand Sánchez, Wendy Roldán, Sergio Villanueva, Mar Bardagí and Lluís Ferrer. Small Demodex populations colonize most parts of the skin of healthy dogs. Veterinary Dermatology 2013, 24: 168-173

Natalia Sastre, Ivan Ravera, Sergio Villanueva, Laura Altet, Mar Bardagí, Armand Sánchez, Olga Francino and Lluís Ferrer. Phylogenetic relationships in three species of canine Demodex mite based on partial sequences of mitochondrial 16S rDNA. Veterinary Dermatology 2012, 23: 509-516

Ravera I, Altet L, Francino O, Bardagí M, Sánchez A, Ferrer L. Development of a real-time PCR to detect Demodex canis DNA in different tissue samples. Parasitol Res. Volumen: 108 Pág:305-308, 2011

Martínez et al. Parasites & Vectors 2011, 4:57, Canine leishmaniasis: the key points for qPCR result interpretation

Salinas M, Francino O, Sánchez A, Altet L. Mycoplasma and herpesvirus PCR detection in tortoises with rhinitis-stomatitis complex in Spain. J Wildl Dis. 2011 Jan;47(1):195-200

M-D. Tabar, R. G. Maggi, L. Altet, M. Vilafranca, O. Francino and X. Roura. Gammopathy in a Spanish dog infected with Bartonella henselae. Journal of Small Animal Practice (2011) 52, 209–212

Carolina Naranjo, Dolors Fondevila, Laura Altet, Olga Francino, José Ríos, Xavier Roura, Teresa Peña. Evaluation of the presence of Leishmania spp. by real-time PCR in the lacrimal glands of dogs with leishmaniosis. The Veterinary Journal 193 (2012) 168–173

Ivan Ravera, Laura Altet, Olga Francino, Mar Bardagí, Armand Sánchez and Lluís Ferrer. Development of a real-time PCR to detect Demodex canis DNA in different tissue samples. Parasitol Res (2011) 108:305–308

Alfredo de la Escosura-Muñiz, Luis Baptista-Pire , Lorena Serrano, Laura Altet, Olga Francino, Armand Sánchez, and Arben Merkoçi. Magnetic Bead/Gold Nanoparticle Double-Labeled Primers for Electrochemical Detection of Isothermal Amplified Leishmania DNA. Small 2016, 12, No. 2, 205–213.

Carmen C. Mayorga-Martinez, Alejandro Chamorro-García, Lorena Serrano, Lourdes Rivasa, Daniel Quesada, Laura Altet, Olga Francino, Armand Sánchez, and Arben Merkoçi. Iridium oxide nanoparticles and polythionine thin film based platform for sensitive Leishmania DNA detection. Journal of Materials Chemistry B, DOI: 10.1039/C5TB00545K

Lourdes Rivas, Alfredo de la Escosura-Muñiz, Lorena Serrano, Laura Altet, Olga Francino, Armand Sánchez, and Arben Merkoçi. Triple lines gold nanoparticle-based lateral flow for enhanced and simultaneous Leishmania DNA detection and endogenous control. Nano Research (2015). DOI 10.1007/s12274-015-0870-3

Nerea Bartolomé, Sergi Segarra, Marta Artieda, Olga Francino, Elisenda Sánchez, Magdalena Szczypiorska, Joaquim Casellas, Diego Tejedor, Joaquín Cerdeira, Antonio Martínez, Alfonso Velasco, Armand Sánchez. A Genetic Predictive Model for Canine Hip Dysplasia: Integration of Genome Wide Association Study (GWAS) and Candidate Gene Approaches. PLoS ONE 04/2015; 10(4):e0122558. DOI: 10.1371/journal.pone.0122558

Anna Cuscó, Armand Sánchez, Laura Altet, Lluís Ferrer and Olga Francino. Non-synonymous genetic variation in exonic regions of canine Toll-like receptors. Canine Genetics and Epidemiology 2014, 1:11

Javier Quilez, Veronica Martinez, John A. Woolliams, Armand Sanchez, Ricardo Pong-Wong, Lorna J. Kennedy, Rupert J. Quinnell, William E. R. Ollier, Xavier Roura, Lluıs Ferrer, Laura Altet, Olga Francino. 2012. Genetic Control of Canine Leishmaniasis: Genome-Wide Association Study and Genomic Selection Analysis. PLoS ONE 7 (4): e35349.

Sastre N, Vilá C, Salinas M, Bologov VV, Urios V, Sanchez A, Francino O, Ramírez O, Signatures of demographic bottlenecks in European wolf populations Conservation Genetics Volumen: en prensa

Javier Quilez, Andrea Short, Verónica Martínez, Lorna Kennedy, William Ollier, Armand Sanchez, Laura Altet, Olga Francino. 2011. A selective sweep of >8 Mb on chromosome 26 in the Boxer genome. BMC Genomics 12: 339.

María Salinas, Laura Altet, Cristina Clavel, Ramón Miguel Almela, Alejandro Bayón, Isabel Burguete, Armand Sánchez. 2011. Genetic assessment, illegal trafficking and management of the Mediterranean spur-thighed tortoise in Southern Spain and Northern Africa. Conservation Genetics 12: 1-13.

2018-2020 – Pathogens And Antimicrobial Resistance: Metagenomics Applied To Personalized Medicine (2017 DI 037 Industrial Doctorate, AGAUR, Generalitat de Catalunya) 27 360 €

2016-2019 – Host genomics and functional metagenomics: homeostasis and resilience in the dog  (2015 DI 044 Industrial Doctorate, AGAUR, Generalitat de Catalunya) 27 360 €

2014-2017 – Genome, microbiome and environment: keeping the homeostasis in a variable world (2013 DI 011 Industrial Doctorate, AGAUR, Generalitat de Catalunya) 27 360 €

2014-2016 – Development and commercialization of a chip for individual identification and detection of parasites in canine feces (can-ID). Line INNCORPORA – TORRES QUEVEDO (PTQ-13-06514).

2012-2014 – Project POC4PETS (FP7-SME-2012-315653-POC4PETS).

2012-2014 – Development of a point of care device for the diagnosis of infectious diseases: canine leishmaniasis as a proof of concept. INNCORPORA-TORRES QUEVEDO (PTQ-11-04766).

2011-2012- Biosensor for the detection of Leishmania infantum DNA. INNOEMPRESA, Ajuts a la innovació per a empreses, ACCIÓ (IEDES-11-1-0063).